A Comparative study of IV Labetalol and IV Hydralazine on mean arterial blood pressure changes in pregnant women with hypertensive emergency
نویسندگان
چکیده
The study was undertaken to compare lowering of blood pressure in pregnant women with hypertensive emergency by IV Labetalol and IV Hydralazine and to find out which drug produces better effect. This prospective type of interventional study was conducted in SMS Medical College, Jaipur among 226 women admitted with SBP ≥ 160 or DBP ≥ 110 mmHg or both. Women divided in 2 groups (113 each) devided randomly: Labetalol (Group-A), Hydralazine (Group-B).We measured the difference between pretreatment and after treatment mean arterial blood pressure. Pretreatment mean arterial blood pressure was 127.40±40 and 126.61±6.475 mmHg in labetalol and Hydralazine group respectively. After treatment mean arterial blood pressure was 112.25±5.821 and 109.27±14.30 mmHg in labetalol and Hydralazine group respectively. Mean arterial blood pressure change was 15.14 ± 8.02 mmHg in labetalol group and 17.34 ± 13.42 mmHg in hydralazine group. (p=0.136, Not significant). Labetalol and Hydralazine both drugs are first line drugs in severe hypertension in pregnancy as in our study both drugs control blood pressure in similar way.
منابع مشابه
Comparison of Hydralazine and Labetalol to lower severe hypertension in pregnancy
OBJECTIVE To compare the intravenous Labetalol versus intravenous hydralazine in patients having severe Pregnancy induced hypertension (PIH) and pre eclampsia (PE) in pregnancy. METHODS Seventy eight women admitted in the Department of Gynecology and Obstetrics, Civil Hospital Karachi, having severe PIH/PE and fulfilling the inclusion criteria were included in the study. Random selection of p...
متن کاملComparison of the effect of two drug combinations of Labetalol-hydralazine and labetalol-trinitroglycerin on hemodynamic factors and bleeding volume during dacryocystorhinostomy
Background: Control of bleeding during dacryocystorhinostomy (DCR) surgery is of particular importance and controlling the body's hemodynamic responses to stress effectively reduces the amount of bleeding during surgery and improves the surgical area. Therefore, in this study, we aimed to investigate the effect of two-drug combinations Labetalol-Hydralazine and Labetalol-Trinitroglycerin on hem...
متن کاملCharacteristics of Patients That Do Not Initially Respond to Intravenous Antihypertensives in the Emergency Department: Subanalysis of the CLUE Trial
INTRODUCTION Hypertensive emergency has a high mortality risk and the treatment goal is to quickly lower blood pressure with intravenous (IV) medications. Characteristics that are associated with non-response to IV antihypertensives have not been identified. The objective is to identify patient characteristics associated with resistance to IV antihypertensives. METHODS This was a subanalysis ...
متن کاملAppropriateness of Bolus Antihypertensive Therapy for Elevated Blood Pressure in the Emergency Department
INTRODUCTION While moderate to severely elevated blood pressure (BP) is present in nearly half of all emergency department (ED) patients, the incidence of true hypertensive emergencies in ED patients is low. Administration of bolus intravenous (IV) antihypertensive treatment to lower BP in patients without a true hypertensive emergency is a wasteful practice that is discouraged by hypertension ...
متن کاملمقایسه اثر فعالیتهای ورزشی هوازی با شدتهای متفاوت بر تغییرات فشارخون زنان میانسال
Background: Physical activity has been recognized as one of the non-pharmacological methods in the treatment of hypertensive disorders. This study aims to compare the effects of aerobic exercise performed and alternative (AI) and constant intensities (CI) in hypertensive individuals. Methods: In this semi-experimental study, subjects were 20 hypertensive women who were asked to fill in the q...
متن کامل